At first I thought this was going to be a work along the lines of Jack London, as it opens with the dog as the narrator. But it quickly moves to a third person perspective (although the changes in intelligence the dog undergoes would make for a challenging first "person" perspective).
The conceit of the story is that by transplanting certain parts (such as the pituitary gland) from a (recently deceased) human into an animal, the animal could gain human form and intelligence. Of course, the newly-human dog behaves exactly the way one would expect (crudely), and sides with his benefactors enemies.
It's an easy read, would recommend.
